Whole-istic Solutions

Creatine has been misunderstood for a long time.

Most women think it is only for bodybuilders or men trying to build muscle.

But here is the truth.

Creatine plays an important role in how women age, and women lose creatine faster than men as we get older.

Creatine supports:
• Muscle strength and maintaining muscle.*
• Brain energy and mental focus.*
• Cellular energy production.*
• Metabolic health.*
• Healthy aging across multiple systems in the body.*
Your body already makes creatine. It is produced in the liver, kidneys, and pancreas and stored primarily in your muscles and brain.

This is one reason creatine has been studied so extensively.

But there is an important shift for women.

As we move through perimenopause and menopause, natural creatine levels decline even more sharply than they do in men.

At the same time we face:
• Hormonal shifts.
• More demand on the brain and nervous system.
• Less efficient energy production inside our cells.
All of this places greater pressure on the systems creatine helps support.

For women over 40, creatine becomes one of the most supportive nutrients for maintaining strength, brain energy, and metabolic resilience as estrogen declines.

NEW!!

Creatine Ultra

with Creavitalis®
Creatine is a natural, endogenous substance that plays an important role in energy metabolism. It has been known for muscle building for years. However, it does so much more and is especially important as we age.

Creatine Ultra provides support where food reaches its limits. It provides optimal creatine balance and pure vitality.

NEW Creatine Ultra improves:
Memory
Sleep Quality
Muscle Mass
Body Composition
Exercise Capacity and Endurance
Bone Mineral Density
Mood
Cognition
Fertility (Egg and s***m count)
Cardiovascular Health

Creatine Ultra is micronized. Micronized powder is ideal for combining with other powders for a healthy drink without grittiness at the bottom of your cup!

20% off
Supplement of the Month

Proteolytic Plus

Our Proteolytic Plus formula includes 9 Proteolytic Enzymes to reduce inflammation.

Inflammation is the body's natural protective response to trauma, but it produces pain and delays healing. To combat pain, people often take medications that inhibit healing and damage the stomach, liver and kidneys.

Proteolytic Plus is the best natural anti -inflammatory with no harmful side effects!

Proteolytic enzymes eat the outer virus coating (called the capsid) which protects a virus. Without the capsid, the virus will die.

Proteolytic enzymes naturally dissolve excess fibrin where viruses commonly hide.

Proteolytic Plus is excellent for preventing all types of inflammation in the body.

Proteolytic Plus can help with congestion due to allergies.

Proteolytic enzymes are scientifically proven to help balance your immune system.

Proteolytic enzymes can promote healthy blood viscosity and platelet aggregation to protect against heart attacks

The Proteolytic enzyme nattokinase acts as an ACE-inhibitor which can lower blood pressure.

The Proteolytic Enzyme nattokinase can break up amyloid fibrils, a type of peptide protein that can build up in the brain and cause cognitive damage that would lead to Alzheimer’s.

Proteolytic Enzymes are able to break down that cause allergies.

Proteolytic Enzymes potentially dissolve blood clots as well as strengthen the arterial walls and improve the quality of blood.

Wishing you a joyful holiday season and a prosperous New Year!

We're sincerely grateful for your continued partnership and trust in us throughout the year.

Wishing you time to recharge and reconnect this holiday season.

Warmest wishes from all of us to you and yours.

Whole-istic Solutions will be closed from December 22 through January 1.

We will return to the office on January 5.

20% off
Super Collagen this month!

Super Collagen makes a healthy holiday gift for friends and family!

Super Collagen:
Supports Bone and Joint Health and Eases Joint Discomfort
Helps Strengthen Hair and Nails
Promotes Younger, Firmer Skin reducing the appearance of fine lines and wrinkles
Improves Gut Function and Digestion
Keeps Excess Inflammation in Check
Builds and Restores Muscle
Revs up your Metabolism
Keeps Appetite In Check
Promotes Healthy Brain Function
Promotes Deeper Sleep

Super Collagen is:
100% Hydrolyzed Collagen
High Bioavailability
Sourced from Brazilian cows that are grass-fed, pasture-raised, and hormone free.
Contains no artificial flavors, additives, or preservatives
Gluten Free
Keto friendly
Kosher
GMO and rBGH: free
Lactose & Dairy Free

Collagen plays a major part in our keeping our skin strong, strengthening muscles and joints, and repairing body tissue. What is less known is how great collagen is for digestive health, and by extension, immune health (70 percent of the immune system is located in the gut). Collagen is comprised of a number of amino acids that have been shown to be beneficial for digestive health. Ours includes all 9 essential Amino Acids.

Super Collagen makes a healthy holiday gift for friends and family!

Why do I need antioxidants?
Primarily because of free radicals. Free radicals are the bi-product of normal energy production in the body. As you breathe, exercise, eat, work and play, your body is producing free radicals. However, our modern way of life tends to increase free radical production. Toxins in air, food and water, as well as electromagnetic radiation and stress, cause free radicals to form in your body. Antioxidants can neutralize free radicals. Free radicals come in many forms and many forms of antioxidants are needed to neutralize them. The best protection is to supplement the diet with a great antioxidant supplement.
Whole-istic Solutions Antioxidant is a complete broad-spectrum antioxidant formula, offering protection from many types of free radicals via a combination of "ready-made" antioxidants and antioxidant precursors. It contains readily absorbable whole-food vitamins, minerals, naturally occurring phytonutrients, enzymes, and botanicals, such as:
Pomegranate Fruit Extract
Citrus Bioflavonoids Complex
Vitamins A, C, and E
Selenium and other minerals
Catechins from green tea
Curcuminoids from turmeric
Proanthocyanidins from grape seed
Alpha lipoic acid
L-glutathione
Digestive enzymes which guarantee the maximum absorption and delivery of all the ingredients in this formula

Liver Support is our Supplement of the Month for April.
20% off

Spring is the ideal time to love your liver!

Spring challenges the liver more than any other season and is the best time to do some liver boosting, cleansing, and detoxifying.

Why cleanse your liver?

Detox your whole body - a clean liver cleans up the rest of your body better and faster.
Increased Energy - cleansing the liver helps maintain the proper supply of nutrients to the body, increasing your energy for exercise and daily activities.
Look and Feel Younger - by reducing toxic buildup in the cells of your body, your skin looks healthier and brighter, and makes it easier for you to tone up, feel great, and look healthier
Weight Loss - the liver is highly instrumental in the breakdown of fat and prevents and Eliminates Stones - the buildup of excess cholesterol causes bile to harden into crystalline stones that create blockages within the liver and the gall bladder. These stones inhibit the liver's ability to detoxify the body, impair the liver's ability to deliver nutrients back to the body, and have been found to cause an imbalance in the body's retention of salt and water.

The herbs and Nutrients in Liver Support have been carefully selected to provide a synergistic benefit for detoxifying the liver and supporting its function.

High-fructose Corn Syrup is Everywhere — Scientists Say It May Make Cancerous Tumors Grow Faster
Consuming fructose boosts the growth of cancerous tumors, according to a new peer-reviewed study. “In some cases, the growth rate of the tumors accelerated by two-fold or even higher,” said the study’s corresponding author Gary Patti, Ph.D.

by Suzanne Burdick, Ph.D.
December 10, 2024

Eating fructose boosts the growth of cancerous tumors — by two-fold or greater in some cases — without changing body weight, fasting glucose or fasting insulin levels, according to a peer-reviewed study published Dec. 4 in Nature.

The authors of the study showed that dietary fructose promotes cancer tumor growth in mice that have melanoma, breast cancer and cervical cancer.

Fructose is a naturally occurring sugar found in some fruits, vegetables, honey and table sugar, according to the Mayo Clinic. The consumption of fructose has greatly increased in recent decades since food and beverage companies started routinely using high-fructose corn syrup as a sweetener, the authors said in their report.

According to the U.S. Food and Drug Administration (FDA), high-fructose corn syrup is derived from corn starch. Corn starch is naturally made of glucose, but added enzymes convert some of the glucose to fructose — which tastes sweeter.

Gary Patti, Ph.D. — a professor of genetics and medicine at Washington University, the senior director for the university’s Center for Metabolomics and Isotope Tracing, and the study’s corresponding author — told The Defender:

“We put animals with cancer on a high-fructose diet and then compared the progression of the disease with animals who were on standard diets. We also fed fructose to cancer cells in a dish.

“We were surprised that dietary fructose drove tumor growth in the animals but that the same cells could not use it as a nutrient when isolated in a dish.”

This led Patti and his co-authors to discover that fructose does not feed tumor growth directly. “Instead, the liver transforms fructose into other nutrients that then drive tumor growth indirectly,” Patti said.

The researchers were also surprised to see how dramatic an impact fructose had on tumors. “In some cases,” Patti said in a press release, “the growth rate of the tumors accelerated by two-fold or even higher … Eating a lot of fructose was clearly very bad for the progression of these tumors.”

The study’s findings raise questions about the role of diet in mitigating cancer. “The idea that you can tackle cancer with diet is intriguing,” said Patti.

Ronald Fowle-Grider, Ph.D., a postdoctoral fellow in Patti’s lab and the study’s first author, told The Defender that added sugars are not needed for a healthy diet — especially added sugars that may promote tumor progression.

“Whether in the context of cancer or not,” he said, “it is important to consider what you are putting into your body, especially non-essential additives such as high fructose corn syrup or cane sugar.”

Liver transforms fructose into nutrients that tumors use

In their report, Patti and his co-authors noted that prior research suggested that fructose promotes tumor growth directly by serving as a fuel, but that’s not what they found was happening.

Fowle-Grider said the researchers initially expected that tumor cells would “metabolize fructose just like glucose, directly utilizing its atoms to build new cellular components such as DNA.”

However, Fowle-Grider said the fructose was “barely metabolized” in the tumor cells that were isolated in a petri dish. “We quickly learned that the tumor cells alone don’t tell the whole story. Equally important is the liver, which transforms fructose into nutrients that the tumors can use.”

After discovering that cancer cells in dishes weren’t enhanced by fructose, the study authors went back to observing molecular changes in the blood of animals fed high-fructose diets.

Using metabolomics, a method of looking at small molecules as they move through cells and across different tissues in the body, they noticed elevated levels of certain lipid species, including lysophosphatidylcholines (LPCs). These lipids are building blocks for cell membranes, the press release said. Cancer cells need them to grow.

The study authors also noticed that when they put liver cells in a dish and fed them fructose, the liver cells released LPCs. This led them to conclude that consuming a lot of fructose indirectly fuels tumor growth by increasing the availability of LPCs in the blood.

Patti explained:

“When we think about tumors, we tend to focus on what dietary components they consume directly. You put something in your body, and then you imagine that the tumor takes it up.

“But humans are complex. What you put in your body can be consumed by healthy tissue and then converted into something else that tumors use.”

The study was partially funded by the National Institutes of Health.

Avoiding high-fructose corn syrup is a challenge — but that could change

The study’s findings suggest that people fighting cancer would benefit from skipping foods and drinks high in fructose, Patti said. “If you are unfortunate enough to have cancer, then you probably want to think about avoiding fructose. Sadly, that is easier said than done.”

Corn is the most heavily subsidized commodity, according to 2023 data reported by nonprofit USA Facts. The federal subsidies artificially lower its price, making byproducts like corn syrup cheaper for food and beverage manufacturers.

High-fructose corn syrup isn’t only added to sweet things like cake or candy. It’s also a common additive to many processed foods, ranging from salad dressing to spaghetti sauce. Soda companies have used it instead of regular sugar for years.

“If you go through your pantry and look for the items that contain high-fructose corn syrup,” Patti said, “which is the most common form of fructose, it is pretty astonishing.”

The average U.S. adult consumes roughly 44 pounds of fructose a year (54.7 grams per day), according to a 2008 study. For adolescents ages 12-18, the average annual fructose intake jumps to nearly 60 pounds (72.8 grams per day.) Newer estimates are unknown.

Those numbers may change if Children’s Health Defense’s former chairman Robert F. Kennedy Jr. is confirmed in January 2025 as secretary of the U.S. Department of Health and Human Services.

Kennedy believes ultraprocessed food is driving the obesity epidemic and contributing to other chronic illnesses in U.S. kids. “When we get President Trump back in the White House and me to Washington,” Kennedy said on Instagram, “we’re going to fix our broken food system and Make America Healthy Again.”

But going after high-fructose corn syrup may meet resistance from U.S. corn growers, The New York Times reported today. Archer Daniels Midland operates one of the Midwest’s largest mills that turn raw corn into high-fructose corn syrup, on the outskirts of Decatur, Illinois. The area is home to other large mills that do the same.

A worker at one of the mills told the Times that Kennedy’s battle against high-fructose corn syrup would have a “huge impact” on the area. “That shuts down Central Illinois, if A.D.M. shuts down,” the worker said.

Additionally, influential billionaires — including Waren Buffet and Bill Gates — benefit from the high-fructose corn syrup industry, which may make large-scale changes in the food and beverage industry’s choice of sweetener more challenging.

Buffet is currently ranked as the world’s eighth-richest person with a net worth of $144.5 billion. He is the CEO and chairman of Berkshire Hathaway, a publicly traded multinational conglomerate company.

An earlier investigation by The Defender revealed that Buffet has vertical investments in various components of the high-fructose corn syrup industry.

The investigation also revealed that Gates benefits indirectly from Buffet’s investments because Berkshire Hathaway is the Bill & Melinda Gates Foundation’s second-top holding.

Suzanne Burdick, Ph.D. is a reporter and researcher for The Defender based in Fairfield, Iowa.

Our supplement of the month, Calcium Plus, is 20% off through the end of October.

Calcium, the most needed and most neglected mineral:

helps protect cardiac muscles
helps prevent kidney stones
has anti-cancer properties
helps control alkaline PH level
helps protect teeth and bones

Because it is often difficult to get enough calcium in your diet, calcium supplementation can be extremely important. Our formula includes not only the most bioavailable forms of calcium and magnesium, but also important nutrients to enhance the delivery of the calcium to the tissues and assist the body with utilization of the nutrients.