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21/12/2023

Masks made of ostrich cells make COVID-19 glow in the dark
Researchers found a way to make the invisible visible.
In the two years that SARS‑CoV‑2 has ravaged across the globe, it has caused immeasurable human loss. But we as a species have been able to create monumental solutions amidst great adversity. The latest achievement involves a standard face mask that can detect COVID-19 in your breath, essentially making the pathogen visible.
Japanese researchers at Kyoto Prefectural University have created a mask that glows in the dark if COVID-19 is detected in a person’s breath or spit. They did this by coating masks with a mixture containing ostrich antibodies that react when they contact the SARS‑CoV‑2 virus. The filters are then removed from the masks and sprayed with a chemical that makes COVID-19 (if present) viewable using a smartphone or a dark light. The experts hope that their discovery could provide a low-cost home test to detect the virus.

Yasuhiro Tsukamoto, veterinary professor and president of Kyoto Prefectural University, explains the benefits of such a technology: “It’s a much faster and direct form of initial testing than getting a PCR test.”

Tsukamoto notes that it could help those infected with the virus but who show no symptoms and are unlikely to get tested — and with a patent application and plans to commercialize inspection kits and sell them in Japan and overseas within the next year, the test appears to have a bright future. However, this all hinges on large-scale testing of the mask filters and government approval for mass production.

Remarkably, this all came with a little help from ostriches.

The ostrich immune system is one of the most potent on Earth
To make each mask, the scientists injected inactive SARS‑CoV‑2 into female ostriches, in effect vaccinating them. Scientists then extracted antibodies from the eggs the ostriches produced, as the yolk transfers immunity to the offspring – the same way a vaccinated mother conveys disease resistance to her infant through the placenta.

An ostrich egg yolk is perfect for this job as it is nearly 24 times bigger than a chicken’s, allowing a more significant number of antibodies to form. Additionally, immune cells are also produced far more quickly in these birds—taking a mere six weeks, as opposed to chickens, where it takes twelve.

Because ostriches have an extremely efficient immune system, thought to be the strongest of any animal on the planet, they can rapidly produce antibodies to fight an enormous range of bacteria and viruses, with a 2012 study in the Brazilian Journal of Microbiology showing they could stop Staphylococcus aureus and E. coli in their tracks – experts also predict that this bird will be instrumental in fending off epidemics in the future.

21/12/2023

Brain scans could help police detect cannabis impairment in drivers
Distinguishing between THC impairment and simple exposure is an urgent need in light of the recent wave of cannabis legalization.
Driving under the influence of psychoactive drugs is a serious offense and a major catalyst for vehicle-related accidents. In order to detect irresponsible drivers and sanction them, law enforcement officers employ various tools such as breath analyzers to detect alcohol in a person’s system or rapid drug tests that can respond to specific markers for co***ne, ma*****na, and other drugs. In the not-so-distant future, road checks could also employ mobile brain scanners that detect particular patterns of neural activity associated with intoxication. Scientists explain how this might work for cannabis impairment in a new study.

Just because you have THC in your system that doesn’t mean you’re not fit to drive
The alcohol content in the blood is closely related to alcohol-related impairment. Even though a breathalyzer indirectly measures the amount of alcohol in one’s breath, a measurement on the handheld device over a certain threshold of intoxication is very closely correlated with the person’s genuine inability to perform well on the road.

There are also breath tests for THC, the main psychoactive ingredient in cannabis, but they’re not reliable for quantitative analyses. They just tell you if someone used ma*****na recently, not how high they actually are. Prosecuting someone who legally used ma*****na the night prior due to having THC detected in their breath the next morning is neither fair nor productive for law enforcement whose resources and man hours are stretched thin as they are.

21/12/2023

Stone toilet in Israel shows that the rich and powerful in antiquity were suffering from parasites
Remember kids: always cook your meat!

The findings are drawn from an archaeological site at the ancient Armon Hanatziv royal estate in Jerusalem. The site lies close to the Dead Sea, to the north of today’s Bethlehem. Analysis of soil samples taken from an ancient toilet found that residents of the estate harbored several intestinal parasites, as evidenced by the discovery of parasitic eggs in the samples.

The findings of this study are among some of the earliest discoveries ever made in Israel up to now.

Egg surprise
“These are durable eggs, and under the special conditions provided by the cesspit, they survived for nearly 2,700 years,” said Dafna Langgut of Tel Aviv University and the Steinhardt Museum of Natural History, a leading researcher in the emerging field of archeoparasitology, and sole author of the study. “Intestinal worms are parasites that cause symptoms like abdominal pain, nausea, diarrhea, and itching. Some of them are especially dangerous for children and can lead to malnutrition, developmental delays, nervous system damage, and, in extreme cases, even death.”

The findings can go a long way towards helping us understand the daily habits of people who once lived in this area, and of how ancient people dealt (or suffered with) infectious disease. This site is particularly valuable in this regard as it showcases the lives of the very rich and wealthy, who were most likely to enjoy the best lifestyle — in regards to resources, practices, and habits — of the time. Sites like this are also relatively hard to get this type of evidence from.

For example, Langgut explains that prior research had compared f***l parasites in hunter-gatherer and farming communities here and elsewhere, helping us better understand what this transition looked like for the people at the time.

One particularly important event for archeoparasitology (the study of parasites throughout human history) is the domestication of animals. At this time, the number of parasitic infections throughout farming communities rose sharply. Hunter-gatherers were generally exposed to fewer parasites and infectious diseases on account of living nomadic lifestyles — this, Langgut adds, is still the case today.

According to the paper, the area Israel occupies today — known as the Fertile Crescent in history — was probably one of the first where human populations suffered from wide-scale intestinal parasitic infection. Various ancient texts have been found throughout Israel referencing such diseases.

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Володимирська вулиця, 12В, Київ
Kyiv