Prolistem - New Azoospermia Treatment

Why is one year of Prolistem® recommended for men with high FSH?

FSH is an indirect indicator of testicular reserve. In general, men with higher FSH levels tend to have fewer remaining s***matogonial stem cells.

Since Prolistem® works by supporting the activation and regeneration of these stem cells, rebuilding a smaller stem cell pool may require more time. That’s why, for men with high FSH, a 12-month Prolistem® program is often recommended to maximize the opportunity for stem cell recovery before s***m retrieval procedures such as microTESE.

More time. More stem cell support. Better potential outcomes.

Individual results vary, and treatment decisions should always be made with a fertility specialist.

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The road to the FIFA World Cup starts with preparation—and for men with non-obstructive azoos***mia, Prolistem® is the preparation that may help improve MicroTESE success. ***mia

Planning a microTESE?

For men with non-obstructive azoos***mia, preparation matters.

Prolistem is specifically designed to be taken before microTESE to help maximize the opportunity for s***m retrieval.

Don’t go straight to surgery without exploring every possibility first.

Visit us at www.prolistem.com

Azoos***mia (zero s***m count) requires a different approach than oligos***mia (low s***m count). That’s why treatments designed for low s***m count may not address the unique challenges faced by men with non-obstructive azoos***mia.

"I Was Told I Have No Stem Cells." Can Prolistem Still Help?

This is an excellent and important question we often hear from patients.
The simple answer is that true complete absence of stem cells (Primary Sertoli Cell-Only Syndrome) is extremely rare. The scientific reality for most men with Non-Obstructive Azoos***mia is far more hopeful.
Here is the truth about

azoos***mia and stem cells:

1. The Science of Hidden Stem Cells
As early as 2010, landmark studies demonstrated the ability to isolate and separate Spermatogonial Stem Cells (SSCs) directly from the testicular tissue of patients with NOA. Since then, multiple research teams have confirmed that even in cases of Sertoli Cell-Only Syndrome (SCOS)—where it appears only support cells remain—men often possess hidden, "focal" pockets of dormant stem cells.

2. How Prolistem Works
Prolistem is designed for these common cases. It does not generate stem cells from scratch. Instead, the treatment is formulated to provide the precise nutritional and biological support needed to "awaken" these dormant stem cells and push them forward to complete the process of s***matogenesis (s***m production).

3. The Rare Exception: Primary SCOS
There is a rare, severe form of SCOS where a patient is born completely devoid of any germ cells (complete germ cell aplasia). This is a condition known as Primary SCOS. In this specific, rare scenario, where no stem cells exist to begin with, no currently known treatment or supplement can create s***m.

The Takeaway

For the vast majority of men diagnosed with Azoos***mia, your stem cells are not missing; they are simply unable to finish their journey. Prolistem aims to provide the trigger they need to finally mature.

Another inspiring Prolistem success story shared by Farah Fertility Center.

After a few months of using Prolistem, 250,000 s***m were successfully detected in the semen analysis of a 30-year-old patient diagnosed with azoos***mia.

The patient previously underwent a bilateral testicular biopsy, which showed no s***m found in either the right or left te**is. Hormonal evaluation was within the normal range, including:
• FSH: 5.72
• LH: 7.81
• Testosterone: 11.59

This case highlights that even patients with previous negative biopsy results may still have hope through new treatment strategies and continuous monitoring.

Special thanks to Dr. Faisal Al Omar from Farah Fertility Center for sharing this successful case.